Enzymatic Bioconversion

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  • Enzymatic Bioconversion

[생물전환기술] 생물전환기술

관리자 2023.09.15 23:29 Inquiry 719

Enzyme-based biomaterial conversion technology 

- Compared to chemical synthesis, biological enzymatic conversion methods use room temperature and pressure, so they consume less energy.

- Enzymes have high specificity and precision, so they do not produce separate by-products, making complex chemical purification steps unnecessary. 

- Biological method has the advantage of being friendly to the human body and the environment. 

- Yeast is used to mass-produce highly active enzymes inexpensively and to ensure economic feasibility of production by repeatedly reusing the enzymes. 


Development case of recombinant lipase CalB1422 ( Candida antarctica lipase B variant 1422)





CalB.jpg



reactor.jpg

View the lipase CalB1422 paper:  https://www.sciencedirect.com/science/article/pii/S0959652623034947



Bioconversion technology for functional oils for cosmetics

- Recently, trends such as eco-friendly cosmetics and clean beauty for ESG management are forming. 
- Most of the basic raw materials for cosmetics manufactured domestically are chemical products produced by large overseas chemical companies.
- To ensure the sustainability of the K-Beauty industry, it is absolutely necessary to localize raw materials and develop and utilize eco-friendly cosmetic materials.  
- We have developed enzyme-based emollient esters for cosmetics, bio-ceramides, and Bio-LSM.

    Enzyme oil product.jpg








Enzyme and fermentation-based biopolymer manufacturing technology 



1. Levan: Produced through enzymatic and fermentation processes
- Fructose polymer with thousands to hundreds of thousands of fructose units linked
- The only water-soluble fructan
- Prebiotics (for human and feed use)
- High molecular weight levan (>2 million kD), low molecular weight levan (~100,000 kD)
- Moisturizer for cosmetics



Levan Shortcut :  http://www.cellapybio.co.kr/?act=board&bbs_code=product&category_code=06&bbs_mode=view&bbs_seq=90






 Yeast Fructan.jpg


View the Yeast Fructan paper:  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9720074/



2. Difructose Anhydrides (DFA-IV, DFA-III): Produced by enzymatic and fermentation processes
- cyclic disaccharides
- Non-digestible, low-calorie sweeteners
- Promotes calcium and iron absorption

DFA4.jpg




View the Yeast DFA-IV paper:  https://www.nature.com/articles/s41598-019-52373-5



3. Medium-chain fructooligosaccharides
   - polymers of 1 glucose and 2 to 23 fructose units
   - produced through yeast fermentation
   - prebiotics for humans and animals
   

MC fructan.jpg


View the Medium-chain oligofructan paper: https://pubmed.ncbi.nlm.nih.gov/31421727/



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